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Data-Guided Precision Dosing

Coarse methods for selecting drug dose can be convenient, but are they appropriate when the stakes are high?

Ensuring health equity for those underrepresented, via safer and more effective drug regimens, tailored to each individual.

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Technology

Introducing DosoLogic.
Precision Pharmacology Software Improving Benefit vs. Risk
when Dosing Critical Therapies

Interpretable Dosing Insights

Empowering decision-makers with best-practice pharmacology modelling via a user-friendly clinical interface. This offers actionable recommendations in areas including oncology, anti-infectives, rheumatology and immunology. 

Seamless Accessiblity

User-led development and integration with prominent electronic health record systems ensures minimal impact to clinical workflows and widespread availability at the point-of-care. 

Maximised Therapeutic Potential

Dose individualization increases the likelihood of achieving target therapeutic effect and minimising drug-related adverse events for each patient. This reduces time in hospital and improves quality of life.

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Getting You to the Right Dose Faster

Combining drug monitoring data with proprietary algorithms, for on-demand predictions of patient response.

How it Works

01.

Data: patient, sample, regimen info, drug & marker levels collected via EHR integration

02.

Modelling: data used to generate drug-specific pharmacology model for patient population

03.

Simulation: model is applied to treatment scenario(s) considering historic patient response

04.

Recommendation:

multiple dosing options offered alongside predicted outcome

05.

Optimisation: real-world data, continuously improves model predictive performance

About

Our Health is Personal.
Why Isn't Our Treatment?

One Size Fits All Dosing

Drug dose selection is guided by patient body weight or surface area. This approach does not fully consider differences between how patient groups process their medication.

Variability in Drug Exposure

Adoption of broad dosing labels can cause unpredictable drug-levels between individuals and patient groups, limiting therapeutic benefit or increasing the likelihood of toxicity.

Quality of Life Impact

Sub-optimal drug exposures causes inequitable outcomes, with 1-in-4 cancer survivors suffering from disease related side effects, costing care providers >$500bn per year.

Partners

Backed by

Newcastle University Centre for Cancer Logo
KQ Labs Accelerator Logo
LifeArc Logo
Grow London Logo
O2H Ventures Logo
UKRI Logo
NIHR Logo
SFC Capital Logo

Hear from future adopters

Pamela Kearns

Professor of Clinical Paediatric Oncology,

University of Birmingham 

“DosoLogic will allow us to individualise the dose of chemotherapy

to maximise effect on the tumour while

minimising the short and long term side effects.”

Leadership

Meet those building the best-in-class precision dosing platform, increasing the likelihood of therapeutic success and driving equity in health outcomes across multiple disease areas.  

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